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| カタログ番号 | HY077013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1793 | ||||
| ターゲット | PCOLC, Mammalian tolloid protein, mTld, Bone morphogenetic protein 1, PCP, BMP-1, Procollagen C-proteinase, BMP1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P13497 | ||||
| RRID | Anti-Human BMP1 Antibody (SAA1793) (abinScience Cat# HY077013, RRID:AB_3727555) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Bone morphogenetic protein 1 (BMP1) is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation. 1. N'Diaye, EN. et al. (2021) American journal of physiology. Cell physiology 320, C162-C174. PMID: 33206546 2. Anastasi, C. et al. (2020) Science signaling 13. PMID: 32636307 3. Wang, J. et al. (2021) Journal of periodontology 92, 1018-1029. PMID: 33169406 4. Rosell-García, T. et al. (2019) The Journal of biological chemistry 294, 11087-11100. PMID: 31152061 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human BMP1 Antibody (SAA1793)
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