Anti-Human BMP10 Recombinant Antibody (SAA0429), APC (HF791237)

Name: Anti-Human BMP10 Recombinant Antibody (SAA0429), APC
Brand: abinScience
SKU: HF791237
Price: 256 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HF791237
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	SAA0429
Conjugaison	APC
Cible	BMP-10, Bone morphogenetic protein 10, BMP10
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Numéro d'accès	O95393
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Bone morphogenetic protein 10 (BMP10) is a ~48 kDa protein. Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human BMP10 Recombinant Antibody (SAA0429), APC.pdf

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