中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HA021013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1910 | ||||
| ターゲット | Von Ebner protein Hl, SPLUNC1, Palate lung and nasal epithelium clone protein, PLUNC, SPURT, Lung-specific protein X, Tracheal epithelium-enriched protein, BPI fold-containing family A member 1, BPIFA1, Secretory protein in upper respiratory tracts, Nasopharyngeal carcinoma-related protein, LUNX, Short PLUNC1, NASG | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9NP55 | ||||
| RRID | Anti-Human BPIFA1/LunX Antibody (SAA1910) (abinScience Cat# HA021013, RRID:AB_3727674) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | BPI fold-containing family A member 1 (BPIFA1/LunX) is a ~26 kDa protein. Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. 1. Ning, F. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 5349-60. PMID: 25223608 2. Sayeed, S. et al. (2013) Infection and immunity 81, 285-91. PMID: 23132494 3. Liu, Y. et al. (2013) The American journal of pathology 182, 1519-31. PMID: 23499554 4. Walton, WG. et al. (2016) Biochemistry 55, 2979-91. PMID: 27145151 5. Garland, AL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15973-8. PMID: 24043776 6. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190 7. Lindahl, M. et al. (2001) Electrophoresis 22, 1795-800. PMID: 11425234 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human BPIFA1/LunX Antibody (SAA1910)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
