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| カタログ番号 | HT375013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human BUB1B Recombinant Antibody (SAA1518) (HT375013) is a mouse monoclonal antibody detecting BUB1B in ELISA. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1518 | ||||
| ターゲット | SSK1, MAD3/BUB1-related protein kinase, BUB1B, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, BUBR1, MAD3L, Protein SSK1, hBUBR1, Mitotic checkpoint kinase MAD3L | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | O60566 | ||||
| RRID | Anti-Human BUB1B Antibody (SAA1518) (abinScience Cat# HT375013, RRID:AB_3727279) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) is a ~119 kDa protein. Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human BUB1B Antibody (SAA1518).
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