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| カタログ番号 | HY106014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human C2 Polyclonal Antibody (HY106014) is a rabbit polyclonal antibody detecting Human C2. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human C2 (Ile245-His451). | ||||||||
| ターゲット | C2, C3/C5 convertase, Complement C2, Complement C2a, EC:3.4.21.43, Serine protease complement C2b | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P06681 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507 3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502 | ||||||||
| 注意事項 | For research use only. |
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