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Anti-Human C3AR1 Recombinant Antibody (SAA0776) (HS803107)

Anti-Human C3AR1 Recombinant Antibody (SAA0776)
Anti-Human C3AR1 Recombinant Antibody (SAA0776)
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Aperçu
Numéro de catalogueHS803107
Reactivité des espècesHuman
ApplicationsELISA, FCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a
ID de cloneSAA0776
Cible AZ3B, HNFAG09, C3AR1, C3R1, C3a-R, C3a anaphylatoxin chemotactic receptor, C3AR
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q16581
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase.

1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936
2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260
3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752
Note For research use only.
Images
  • Anti-Human C3AR1 Recombinant Antibody (SAA0776)

    SDS-PAGE

    SDS-PAGE for Anti-Human C3AR1 Antibody (SAA0776)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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