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| カタログ番号 | HS803107 |
|---|---|
| 種反応性 | Human |
| アプリケーション | ELISA, FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a |
| クローンID | SAA0776 |
| ターゲット | AZ3B, HNFAG09, C3AR1, C3R1, C3a-R, C3a anaphylatoxin chemotactic receptor, C3AR |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q16581 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.09% Sodium azide. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase. 1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936 2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260 3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human C3AR1 Antibody (SAA0776)
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