Anti-Human C7 Recombinant Antibody (SAA1569) (HY181013)

Name: Anti-Human C7 Recombinant Antibody (SAA1569)
Brand: abinScience
SKU: HY181013
Price: 196 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HY181013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1569

Цель

C7, Complement component C7

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P10643

RRID

Anti-Human C7 Antibody (SAA1569) (abinScience Cat# HY181013, RRID:AB_3727330)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Complement component C7 (Complement C7) is a ~93 kDa protein. Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C7 serves as a membrane anchor. During MAC assembly, associates with C5b and C6 to form the C5b-7 complex, a key lipophilic precursor of the MAC complex, which associates with the outer leaflet and reduces the energy for membrane bending.

1. Hadders, MA. et al. (2012) Cell reports 1, 200-7. PMID: 22832194

2. Serna, M. et al. (2016) Nature communications 7, 10587. PMID: 26841837

3. Sharp, TH. et al. (2016) Cell reports 15, 1-8. PMID: 27052168

4. Menny, A. et al. (2018) Nature communications 9, 5316. PMID: 30552328

5. DiScipio, RG. et al. (1988) The Journal of biological chemistry 263, 549-60. PMID: 3335508

6. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456

7. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human C7 Antibody (SAA1569)

Ссылки

Даташит

Anti-Human C7 Recombinant Antibody (SAA1569).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа