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Anti-Human CA4 Polyclonal Antibody (HB731014)

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Vista general
Número de catálogoHB731014
Descripción
Anti-Human CA4 Polyclonal Antibody (HB731014) is a rabbit polyclonal antibody detecting CA4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CA4 (Ala19-Lys283).
Objetivo Carbonic anhydrase 4, Carbonate dehydratase IV, CA-IV, CA4, Carbonic anhydrase IV
Purificación Purified by antigen affinity column.
Número de acceso P22748
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Carbonic anhydrase 4 (CA4) is a ~35 kDa protein. Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.

1. Yang, Z. et al. (2005) Human molecular genetics 14, 255-65. PMID: 15563508
2. Temperini, C. et al. (2006) Journal of medicinal chemistry 49, 3019-27. PMID: 16686544
3. Temperini, C. et al. (2006) Chemistry (Weinheim an der Bergstrasse, Germany) 12, 7057-66. PMID: 16807956
4. Temperini, C. et al. (2007) Bioorganic & medicinal chemistry letters 17, 628-35. PMID: 17127057
5. Temperini, C. et al. (2007) Bioorganic & medicinal chemistry letters 17, 2210-5. PMID: 17314045
6. Alvarez, BV. et al. (2007) Investigative ophthalmology & visual science 48, 3459-68. PMID: 17652713
7. Köhler, K. et al. (2007) Angewandte Chemie (International ed. in English) 46, 7697-9. PMID: 17705204
8. Di Fiore, A. et al. (2009) Proteins 74, 164-75. PMID: 18618712
9. Crocetti, L. et al. (2009) Bioorganic & medicinal chemistry letters 19, 1371-5. PMID: 19186056
10. Maresca, A. et al. (2009) Journal of the American Chemical Society 131, 3057-62. PMID: 19206230
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human CA4 Polyclonal Antibody

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