Anti-Human CADM1 Recombinant Antibody (SAA1897) (HA183013)

Name: Anti-Human CADM1 Recombinant Antibody (SAA1897)
Brand: abinScience
SKU: HA183013
Price: 110 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HA183013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1897

Objetivo

SgIgSF, Immunoglobulin superfamily member 4, SynCAM, IGSF4A, SYNCAM, TSLC1, Synaptic cell adhesion molecule, IgSF4, Tumor suppressor in lung cancer 1, TSLC-1, CADM1, Spermatogenic immunoglobulin superfamily, Nectin-like protein 2, Cell adhesion molecule 1, NECL2, IGSF4, NECL-2

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9BY67

RRID

Anti-Human CADM1 Antibody (SAA1897) (abinScience Cat# HA183013, RRID:AB_3727661)
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Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Cell adhesion molecule 1 (CADM1) is a ~48 kDa protein. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo.

1. Masuda, M. et al. (2002) The Journal of biological chemistry 277, 31014-9. PMID: 12050160

2. Moiseeva, EP. et al. (2012) Cellular and molecular life sciences : CMLS 69, 2751-64. PMID: 22438059

3. Boles, KS. et al. (2005) Blood 106, 779-86. PMID: 15811952

4. Furuno, T. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 6934-42. PMID: 15905536

5. Kuramochi, M. et al. (2001) Nature genetics 27, 427-30. PMID: 11279526

6. Yageta, M. et al. (2002) Cancer research 62, 5129-33. PMID: 12234973

7. Ito, A. et al. (2003) Laboratory investigation; a journal of technical methods and pathology 83, 1175-83. PMID: 12920246

Nota

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human CADM1 Antibody (SAA1897)

Referencias

Datasheet

Anti-Human CADM1 Recombinant Antibody (SAA1897).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo