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| カタログ番号 | HA183013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1897 | ||||
| ターゲット | SgIgSF, Immunoglobulin superfamily member 4, SynCAM, IGSF4A, SYNCAM, TSLC1, Synaptic cell adhesion molecule, IgSF4, Tumor suppressor in lung cancer 1, TSLC-1, CADM1, Spermatogenic immunoglobulin superfamily, Nectin-like protein 2, Cell adhesion molecule 1, NECL2, IGSF4, NECL-2 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9BY67 | ||||
| RRID | Anti-Human CADM1 Antibody (SAA1897) (abinScience Cat# HA183013, RRID:AB_3727661) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Cell adhesion molecule 1 (CADM1) is a ~48 kDa protein. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. 1. Masuda, M. et al. (2002) The Journal of biological chemistry 277, 31014-9. PMID: 12050160 2. Moiseeva, EP. et al. (2012) Cellular and molecular life sciences : CMLS 69, 2751-64. PMID: 22438059 3. Boles, KS. et al. (2005) Blood 106, 779-86. PMID: 15811952 4. Furuno, T. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 6934-42. PMID: 15905536 5. Kuramochi, M. et al. (2001) Nature genetics 27, 427-30. PMID: 11279526 6. Yageta, M. et al. (2002) Cancer research 62, 5129-33. PMID: 12234973 7. Ito, A. et al. (2003) Laboratory investigation; a journal of technical methods and pathology 83, 1175-83. PMID: 12920246 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human CADM1 Antibody (SAA1897)
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