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| カタログ番号 | HY028013 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||
| アプリケーション | ELISA, WB | ||||||
| 宿主種 | Human | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG4, kappa | ||||||
| クローンID | SAA2004 | ||||||
| ターゲット | Alpha-type CGRP, CALC1, CALCA, CGRP-I, CGRP1, Calcitonin gene-related peptide 1, Calcitonin gene-related peptide I | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | P06881 | ||||||
| RRID | Anti-Human CALCA Antibody (SAA2004) (abinScience Cat# HY028013, RRID:AB_3727916) |
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| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Calcitonin gene-related peptide 1 (CGRP1) is a ~13 kDa protein. CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex. 1. Kitamura, K. et al. (1992) Biochemical and biophysical research communications 185, 134-41. PMID: 1318039 2. Josephs, TM. et al. (2021) Science (New York, N.Y.) 372. PMID: 33602864 3. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797 4. Petermann, JB. et al. (1987) The Journal of biological chemistry 262, 542-5. PMID: 3492492 5. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770 | ||||||
| 注意事項 | For research use only. | ||||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SDS-PAGE for Anti-Human CALCA Antibody (SAA2004).
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