Anti-Human CALCRL Recombinant Antibody (SAA0150), FITC (HS841117)

Name: Anti-Human CALCRL Recombinant Antibody (SAA0150), FITC
Brand: abinScience
SKU: HS841117
Price: 223 USD
Availability: InStock

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Каталожный номер	HS841117
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG2, lambda
ID клона	SAA0150
Конъюгация	FITC
Цель	CGRP type 1 receptor, CGRPR, Calcitonin receptor-like receptor, CALCRL, Calcitonin gene-related peptide type 1 receptor
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Номер доступа	Q16602
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Calcitonin gene-related peptide type 1 receptor (CALCRL) is a ~52 kDa protein. G protein-coupled receptor which specificity is determined by its interaction with receptor-activity-modifying proteins (RAMPs). Together with RAMP1, form the receptor complex for calcitonin-gene-related peptides CALCA/CGRP1 and CALCB/CGRP2. Together with RAMP2 or RAMP3, function as receptor complexes for adrenomedullin (ADM and ADM2). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Liang, YL. et al. (2020) ACS pharmacology & translational science 3, 263-284. PMID: 32296767 2. Josephs, TM. et al. (2021) Science (New York, N.Y.) 372. PMID: 33602864 3. Aiyar, N. et al. (1996) The Journal of biological chemistry 271, 11325-9. PMID: 8626685 4. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CALCRL Recombinant Antibody (SAA0150), FITC.pdf

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