Anti-Human CAMLG Polyclonal Antibody (HW596014)

Name: Anti-Human CAMLG Polyclonal Antibody
Brand: abinScience
SKU: HW596014
Price: 96 USD
Availability: InStock

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Каталожный номер

HW596014

Описание

Anti-Human CAMLG Polyclonal Antibody (HW596014) is a rabbit polyclonal antibody detecting CAMLG in ELISA, IHC, WB. Suitable for Mus musculus and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CAMLG (Gly19-Glu184).

Цель

CAMLG

Очистка

Purified by antigen affinity column.

Номер доступа

P49069

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

Guided entry of tail-anchored proteins factor CAMLG, Calcium signal-modulating cyclophilin ligand, CAMLG, CAML, GET2

Фон

Guided entry of tail-anchored proteins factor CAMLG is a ~32 kDa protein. Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

1. Yamamoto, Y. et al. (2012) Molecular cell 48, 387-97. PMID: 23041287

2. Vilardi, F. et al. (2014) PloS one 9, e85033. PMID: 24392163

3. Colombo, SF. et al. (2016) The Journal of biological chemistry 291, 15292-306. PMID: 27226539

4. Inglis, AJ. et al. (2020) Cell reports 30, 3691-3698.e5. PMID: 32187542

5. Bram, RJ. et al. (1994) Nature 371, 355-8. PMID: 7522304

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-CAMLG polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: 293T cell lysate
Lane 3: Mouse testis lysate
Lane 4: Mouse brain lysate

Ссылки

Даташит

Anti-Human CAMLG Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human CAMLG Polyclonal Antibody (HW596014)

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Изображения

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