Anti-Human CASP9/Caspase 9 Monoclonal Antibody (1A127) (HX251025)

Name: Anti-Human CASP9/Caspase 9 Monoclonal Antibody (1A127)
Brand: abinScience
SKU: HX251025
Price: 106 USD
Availability: InStock

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Numéro de catalogue	HX251025
Description	Anti-Human CASP9/Caspase 9 Monoclonal Antibody (1A127) [1A127] (HX251025) is a mouse monoclonal antibody detecting Caspase-9 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, IHC, WB
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	1A127
Immunogène	E. coli - derived recombinant Human CASP9 / Caspase 9 (Lys100-Thr270).
Cible	CASP9, ICE-like apoptotic protease 6, Apoptotic protease Mch-6, APAF-3, CASP-9, MCH6, Apoptotic protease-activating factor 3, Caspase-9, ICE-LAP6,
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P55211
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Caspase-9 (CASP9/Caspase 9) is a ~46 kDa protein. Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC. 1. Ehrmann, JF. et al. (2023) Science (New York, N.Y.) 379, 1117-1123. PMID: 36758105 2. Dietz, L. et al. (2023) Science (New York, N.Y.) 379, 1112-1117. PMID: 36758106
Note	For research use only.

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Anti-Human CASP9/Caspase 9 Monoclonal Antibody (1A127).pdf

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Anti-Human CASP9/Caspase 9 Monoclonal Antibody (1A127) (HX251025)

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