Anti-Human CBS Polyclonal Antibody (HW451014)

Name: Anti-Human CBS Polyclonal Antibody
Brand: abinScience
SKU: HW451014
Price: 168 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW451014

Description

Anti-Human CBS Polyclonal Antibody (HW451014) is a rabbit polyclonal antibody detecting CBS in ELISA, IHC, WB. Suitable for Human, Mouse, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CBS (Lys72-Lys551).

Cible

Serine sulfhydrase, CBS, Cystathionine beta-synthase, Beta-thionase

Purification

Purified by antigen affinity column.

Numéro d'accès

P35520

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Cystathionine beta-synthase (CBS) is a ~60 kDa protein. Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.

1. Kozich, V. et al. (2010) Human mutation 31, 809-19. PMID: 20506325

2. Mendes, MI. et al. (2014) Journal of inherited metabolic disease 37, 245-54. PMID: 23974653

3. Casique, L. et al. (2013) Gene 531, 117-24. PMID: 23981774

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human CBS Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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