Anti-Human CBX6 Polyclonal Antibody (HF624014)

Name: Anti-Human CBX6 Polyclonal Antibody
Brand: abinScience
SKU: HF624014
Price: 168 USD
Availability: InStock

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HF624014

Description

Anti-Human CBX6 Polyclonal Antibody (HF624014) is a rabbit polyclonal antibody detecting CBX6 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CBX6 (Met1-Lys412).

Cible

Chromobox protein homolog 6, CBX6

Purification

Purified by antigen affinity column.

Numéro d'accès

O95503

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Chromobox protein homolog 6 (CBX6) is a ~43 kDa protein. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3-independent fashion. May have a PRC1-independent function in embryonic stem cells.

1. Vandamme, J. et al. (2011) Molecular & cellular proteomics : MCP 10, M110.002642. PMID: 21282530

2. Vincenz, C. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 16572-7. PMID: 18927235

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human CBX6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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