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Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456) (HY346107)

Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)
Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)
Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)
Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)
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  • 概要

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  • データシート

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概要
カタログ番号HY346107
種反応性Human
アプリケーションELISA, FCM, WB
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG2a
クローンIDSAA0456
ターゲット TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P13501
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.09% Sodium azide.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064
2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218
3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620
4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373
5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414
6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485
注意事項 For research use only.
イメージ
  • Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)

    Western blot

    Western blot analysis was performed using anti-CCL5/RANTES monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CCL5/RANTES (Catalog No: HY346012)
    Lane 2: negative control

  • Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)

    Bioactivity

    Detects recombinant human CCL5/RANTES (Catalog No: HY346012) in indirect ELISA

参考文献
Formula
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