Anti-Human CCT3 Polyclonal Antibody (HW312014)

Name: Anti-Human CCT3 Polyclonal Antibody
Brand: abinScience
SKU: HW312014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HW312014

Description

Anti-Human CCT3 Polyclonal Antibody (HW312014) is a rabbit polyclonal antibody detecting CCT3 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CCT3 (Lys15-Lys527).

Cible

hTRiC5, CCT-gamma, T-complex protein 1 subunit gamma, TCP-1-gamma, CCTG, TRIC5, CCT3

Purification

Purified by antigen affinity column.

Numéro d'accès

P49368

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

T-complex protein 1 subunit gamma (CCT3) is a ~60 kDa protein. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.

1. Freund, A. et al. (2014) Cell 159, 1389-403. PMID: 25467444

2. Gestaut, D. et al. (2022) Cell 185, 4770-4787.e20. PMID: 36493755

3. Kelly, JJ. et al. (2022) Nature structural & molecular biology 29, 420-429. PMID: 35449234

4. Liu, C. et al. (2023) Communications biology 6, 531. PMID: 37193829

5. Seo, S. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 1488-93. PMID: 20080638

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human CCT3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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