Anti-Human CD106/VCAM1 Recombinant Antibody (H6), PerCP (HB032247)

Name: Anti-Human CD106/VCAM1 Recombinant Antibody (H6), PerCP
Brand: abinScience
SKU: HB032247
Price: 268 USD
Availability: InStock

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Каталожный номер	HB032247
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Rabbit
Клоональность	Monoclonal
Изотип	IgG
ID клона	H6
Конъюгация	PerCP
Цель	Vascular cell adhesion protein 1, VCAM1, CD106, INCAM-100, V-CAM 1, VCAM-1
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Rabbit IgG Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Номер доступа	P19320
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Vascular cell adhesion protein 1 (CD106/VCAM1) is a ~81 kDa protein. Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Also serves as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation. 1. Li, Y. et al. (2020) Journal of molecular cell biology 12, 190-201. PMID: 31310649 2. Taooka, Y. et al. (1999) The Journal of cell biology 145, 413-20. PMID: 10209034 3. Marchese, ME. et al. (2012) Biochemistry 51, 8235-46. PMID: 22970700 4. Pinho, S. et al. (2022) Nature cell biology 24, 290-298. PMID: 35210567
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD106/VCAM1 Recombinant Antibody (H6), PerCP.pdf

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