Anti-Human CD106/VCAM1 Recombinant Nanobody (cAbVCAM1-5) (HB032023)

Name: Anti-Human CD106/VCAM1 Recombinant Nanobody (cAbVCAM1-5)
Brand: abinScience
SKU: HB032023
Price: 126 USD
Availability: InStock

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Цена(USD):

Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HB032023

Описание

Anti-Human CD106/VCAM1 Nanobody (cAbVCAM1-5) [cAbVCAM1-5] (HB032023) is a alpaca monoclonal antibody detecting VCAM1 in ELISA, FuncS. Suitable for Human and Mouse.

Реактивность видов

Human, Mouse

Применения

ELISA, FuncS

Хозяинский вид

Alpaca

Клоональность

Monoclonal

Изотип

VHH-8His-Cys-tag

ID клона

cAbVCAM1-5

Цель

Vascular cell adhesion protein 1, VCAM1, CD106, INCAM-100, V-CAM 1, VCAM-1

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Purified by Nickel column.

Номер доступа

P19320

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Vascular cell adhesion protein 1 (CD106/VCAM1) is a ~81 kDa protein. Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Also serves as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.

1. Li, Y. et al. (2020) Journal of molecular cell biology 12, 190-201. PMID: 31310649

2. Taooka, Y. et al. (1999) The Journal of cell biology 145, 413-20. PMID: 10209034

3. Marchese, ME. et al. (2012) Biochemistry 51, 8235-46. PMID: 22970700

4. Pinho, S. et al. (2022) Nature cell biology 24, 290-298. PMID: 35210567

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human CD106/VCAM1 Nanobody (cAbVCAM1-5)

Ссылки

Даташит

Anti-Human CD106/VCAM1 Recombinant Nanobody (cAbVCAM1-5).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа