Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107) (HY474107)

Name: Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107)
Brand: abinScience
SKU: HY474107
Price: 118 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HY474107
Reactivité des espèces	Human
Applications	Blocking, DB, FCM, IHC
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	mAb107
Cible	CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P11215
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain. 1. Losse, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 912-21. PMID: 20008295 2. DiScipio, RG. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 4057-66. PMID: 9558116 3. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980 4. Jerke, U. et al. (2011) The Journal of biological chemistry 286, 7070-81. PMID: 21193407 5. Diamond, MS. et al. (1990) The Journal of cell biology 111, 3129-39. PMID: 1980124
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human CD11b/ITGAM Antibody (mAb107).

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Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107).pdf

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Formula

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