Anti-Human TNF RII/TNFRSF1B Recombinant Antibody (E4#), APC (HB070137)

Name: Anti-Human TNF RII/TNFRSF1B Recombinant Antibody (E4#), APC
Brand: abinScience
SKU: HB070137
Price: 290 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50T
100T

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	HB070137
Реактивность видов	Human
Применения	ELISA, FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	E4#
Конъюгация	APC
Цель	TNF-R2, TNFR-II, p80 TNF-alpha receptor, Etanercept, TNFBR, TBP-2, TBPII, Tumor necrosis factor receptor superfamily member 1B, CD120b, p75, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNFR2, Tumor necrosis factor receptor type II
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Номер доступа	P20333
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFR2) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
Ссылки	1. Goffe B, et al. Etanercept: An overview. J Am Acad Dermatol. 2003;49(2 Suppl):S105-S111. [HB070137] 2. Goldenberg MM. Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis. Clin Ther. 1999;21(1):75-2. [HB070137] 3. Haraoui B, et al. Etanercept in the treatment of rheumatoid arthritis. Ther Clin Risk Manag. 2007;3(1):99-105. [HB070137] 4. Totoson P, et al. Etanercept improves endothelial function via pleiotropic effects in rat adjuvant-induced arthritis. Rheumatology (Oxford). 2016;55(7):1308-1317. View More [HB070137]
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.