Please ensure Javascript is enabled for purposes of website accessibility
Главная > Продукты > Антитела > Первичные Антитела
Anti-Human CD14 Recombinant Nanobody (SAA2077)
Anti-Human CD14 Recombinant Nanobody (SAA2077)
Цена(USD):
Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
Свяжитесь с нами
  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHY038033
Описание
Anti-Human CD14 Nanobody (SAA2077) [SAA2077] (HY038033) is a alpaca monoclonal antibody detecting CD14 in ELISA. Suitable for Human.
Реактивность видовHuman
ПримененияELISA
Хозяинский видAlpaca
КлоональностьMonoclonal
ИзотипVHH-8His-Cys-tag
ID клонаSAA2077
Цель CD14, Monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14, membrane-bound form, Monocyte differentiation antigen CD14, urinary form, My23 antigen, Myeloid cell-specific leucine-rich glycoprotein
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Purified by Nickel column.
Номер доступа P08571
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Monocyte differentiation antigen CD14 is a ~40 kDa protein. Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).

1. Wright, SD. et al. (1990) Science (New York, N.Y.) 249, 1431-3. PMID: 1698311
2. Kelley, SL. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 1304-11. PMID: 23264655
3. Tsukamoto, H. et al. (2010) International immunology 22, 271-80. PMID: 20133493
4. Murakami, K. et al. (2012) FEBS letters 586, 319-24. PMID: 22265692
5. Haziot, A. et al. (1996) Immunity 4, 407-14. PMID: 8612135
6. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211
7. Estruch, M. et al. (2013) Atherosclerosis 229, 356-62. PMID: 23880187
Примечание For research use only.
Изображения
  • Anti-Human CD14 Recombinant Nanobody (SAA2077)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD14 Nanobody (SAA2077)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.

Почта: [email protected]

Список дистрибьюторов