Anti-Human ALCAM/CD166 Polyclonal Antibody (HC678014)

Name: Anti-Human ALCAM/CD166 Polyclonal Antibody
Brand: abinScience
SKU: HC678014
Price: 168 USD
Availability: InStock

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100ug

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HC678014

説明

Anti-Human CD166/ALCAM Polyclonal Antibody (HC678014) is a rabbit polyclonal antibody detecting ALCAM. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human CD166/ALCAM (Trp28-Lys527).

ターゲット

ALCAM, Activated leukocyte cell adhesion molecule, CD166, CD166 antigen, MEMD

エンドトキシンレベル

Please contact with the lab for this information.

精製

Purified by antigen affinity column.

アクセッション番号

Q13740

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation.

1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703

2. Ikeda, K. et al. (2004) The Journal of biological chemistry 279, 55315-23. PMID: 15496415

3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806

4. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771

5. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728

6. Bowen, MA. et al. (1995) The Journal of experimental medicine 181, 2213-20. PMID: 7760007

7. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938

8. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213

9. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813

注意事項

For research use only

イメージ

Western blot

Western blot analysis was performed using anti-ALCAM polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: U2OS cell lysate

参考文献

データシート

Anti-Human ALCAM/CD166 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human ALCAM/CD166 Polyclonal Antibody (HC678014)

概要

イメージ

参考文献

データシート

SDS