

| Каталожный номер | HC282137 |
|---|---|
| Реактивность видов | Human |
| Применения | FCM |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| ID клона | 2004# |
| Конъюгация | APC |
| Цель | Protein-tyrosine kinase RTK-6, Protein-tyrosine kinase 3A, NTRK4, EDDR1, CAK, Tyrosine kinase DDR, Mammary carcinoma kinase 10, TRKE, Epithelial discoidin domain-containing receptor 1, CD167a, TRK E, Epithelial discoidin domain receptor 1, HGK2, CD167 antigen-like family member A, NEP, MCK-10, Tyrosine-protein kinase CAK, PTK3A, DDR1, Discoidin receptor tyrosine kinase, RTK6, Cell adhesion kinase |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Связанные продукты | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| Номер доступа | Q08345 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Фон | Epithelial discoidin domain-containing receptor 1 (CD167a/DDR1) is a ~101 kDa protein. Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing. |
| Примечание | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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