



| Número de catálogo | HB243107 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | FCM |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | 3H9 |
| Objetivo | IL8RB, GRO/MGSA receptor, C-X-C chemokine receptor type 2, CD182, CXCR-2, IL-8R B, CXC-R2, IL-8 receptor type 2, High affinity interleukin-8 receptor B, CDw128b, CXCR2 |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P25025 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Fondo | C-X-C chemokine receptor type 2 (CD182/CXCR2) is a ~40 kDa protein. Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. 1. Murphy, PM. et al. (1991) Science (New York, N.Y.) 253, 1280-3. PMID: 1891716 2. Damaj, BB. et al. (1996) The Journal of biological chemistry 271, 12783-9. PMID: 8662698 |
| Nota | For research use only. |

SEC-HPLC detection for Anti-Human CD182/CXCR2 Antibody (3H9).

Flow-cytometry using anti-human CD182 antibody. U937 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD182 monoclonal antibody (Catalog: HB243107, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.




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