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Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9) (HB243107)

Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9)
Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9)
Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9)
Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9)
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  • 概要

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  • 参考文献

  • データシート

  • SDS

概要
カタログ番号HB243107
種反応性Human
アプリケーションFCM
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンID3H9
ターゲット IL8RB, GRO/MGSA receptor, C-X-C chemokine receptor type 2, CD182, CXCR-2, IL-8R B, CXC-R2, IL-8 receptor type 2, High affinity interleukin-8 receptor B, CDw128b, CXCR2
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P25025
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

C-X-C chemokine receptor type 2 (CD182/CXCR2) is a ~40 kDa protein. Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

1. Murphy, PM. et al. (1991) Science (New York, N.Y.) 253, 1280-3. PMID: 1891716
2. Damaj, BB. et al. (1996) The Journal of biological chemistry 271, 12783-9. PMID: 8662698
注意事項 For research use only.
イメージ
  • Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD182/CXCR2 Antibody (3H9).

  • Anti-Human CXCR2/IL-8RB Recombinant Antibody (3H9)

    Flow CytoMetry

    Flow-cytometry using anti-human CD182 antibody. U937 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD182 monoclonal antibody (Catalog: HB243107, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
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