Anti-Human CD192/CCR2 Recombinant Antibody (1D9), FITC (HW392117)

Name: Anti-Human CD192/CCR2 Recombinant Antibody (1D9), FITC
Brand: abinScience
SKU: HW392117
Price: 223 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50T
100T

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HW392117
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	1D9
Conjugación	FITC
Objetivo	CCR2, CC-CKR-2, C-C chemokine receptor type 2, CCR-2, C-C CKR-2, MCP-1-R, CMKBR2, CD192, Monocyte chemoattractant protein 1 receptor
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
Número de acceso	P41597
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	C-C chemokine receptor type 2 (CD192/CCR2) is a ~41 kDa protein. Key functional receptor for CCL2 but can also bind CCL7, and CCL12. Also transduces signaling mediated by CCL13. Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion. Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B. Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation. 1. Tan, JHY. et al. (2013) The Journal of biological chemistry 288, 10024-10034. PMID: 23408426 2. Neehus, AL. et al. (2024) Cell 187, 390-408.e23. PMID: 38157855 3. Yamagami, S. et al. (1994) Biochemical and biophysical research communications 202, 1156-62. PMID: 8048929 4. Charo, IF. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 2752-6. PMID: 8146186 5. De Paula, VS. et al. (2013) Journal of molecular biology 425, 4479-95. PMID: 23938203
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Imágenes

Referencias

Datasheet

Anti-Human CD192/CCR2 Recombinant Antibody (1D9), FITC.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo