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| カタログ番号 | HF719107 |
|---|---|
| 種反応性 | Human |
| アプリケーション | FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | 3131# |
| ターゲット | AcPL, Accessory protein-like, Interleukin-1 receptor 7, IL-18R-beta, CD218 antigen-like family member B, IL-1RAcPL, Interleukin-18 receptor accessory protein, CDw218b, IL-1R-7, IL1R7, IL-1R7, IL-18RAcP, CD218b, IL-1R accessory protein-like, IL18RAP, Interleukin-18 receptor accessory protein-like, IL-18 receptor accessory protein, IL-18Rbeta, Interleukin-18 receptor beta |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | O95256 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649 |
| 注意事項 | For research use only. |
Detects Human CD218b/IL18RAP in indirect ELISAs.
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