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Anti-Human CD23 Recombinant Antibody (MHM6), APC (HY541237)

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Aperçu
Numéro de catalogueHY541237
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a
ID de cloneMHM6
ConjugaisonAPC
Cible Lymphocyte IgE receptor, C-type lectin domain family 4 member J, Low affinity immunoglobulin epsilon Fc receptor, CD23A, BLAST-2, Immunoglobulin E-binding factor, IGEBF, CD23, Fc-epsilon-RII, CLEC4J, FCE2, FCER2
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Numéro d'accès P06734
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Low affinity immunoglobulin epsilon Fc receptor (CD23/FCER2) is a ~36 kDa protein. Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.

1. Pirron, U. et al. (1990) European journal of immunology 20, 1547-51. PMID: 2167225
2. Vouldoukis, I. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 7804-8. PMID: 7544003
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Recommandation

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