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| カタログ番号 | HF626137 |
|---|---|
| 種反応性 | Human |
| アプリケーション | FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | C4201 |
| 抱合 | APC |
| ターゲット | Anion exchange protein 1, Anion exchanger 1, EPB3, CD233, Band 3 anion transport protein, AE 1, DI, AE1, SLC4A1, Solute carrier family 4 member 1 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| アクセッション番号 | P02730 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Band 3 anion transport protein (CD233/SLC4A1) is a ~101 kDa protein. Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. 1. Bruce, LJ. et al. (2000) The Biochemical journal 350 Pt 1, 41-51. PMID: 10926824 2. Rungroj, N. et al. (2004) The Journal of biological chemistry 279, 13833-8. PMID: 14734552 3. Schofield, AE. et al. (1992) Journal of molecular biology 223, 949-58. PMID: 1538405 4. Bruce, LJ. et al. (2005) Nature genetics 37, 1258-63. PMID: 16227998 5. Ungsupravate, D. et al. (2010) Molecular membrane biology 27, 92-103. PMID: 20151848 6. Shnitsar, V. et al. (2013) The Journal of biological chemistry 288, 33848-33860. PMID: 24121512 7. Genetet, S. et al. (2017) Scientific reports 7, 46170. PMID: 28387307 8. Vallese, F. et al. (2022) Nature structural & molecular biology 29, 706-718. PMID: 35835865 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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