Anti-Human CD245/MYO18A Recombinant Antibody (DY12), APC (HV061137)

Name: Anti-Human CD245/MYO18A Recombinant Antibody (DY12), APC
Brand: abinScience
SKU: HV061137
Price: 290 USD
Availability: InStock

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概要

カタログ番号	HV061137
種反応性	Human
アプリケーション	FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	DY12
抱合	APC
ターゲット	CD245, Myosin containing a PDZ domain, MAJN, SP-R210, Surfactant protein receptor SP-R210, MYO18A, MYSPDZ, Unconventional myosin-XVIIIa, KIAA0216, Molecule associated with JAK3 N-terminus
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
アクセッション番号	Q92614
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Unconventional myosin-XVIIIa (CD245/MYO18A) is a ~233 kDa protein. May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. 1. Dippold, HC. et al. (2009) Cell 139, 337-51. PMID: 19837035 2. Ng, MM. et al. (2013) Molecular biology of the cell 24, 796-808. PMID: 23345592 3. Tan, I. et al. (2008) Cell 135, 123-36. PMID: 18854160 4. Yang, L. et al. (2015) PloS one 10, e0126576. PMID: 25965346 5. Yang, CH. et al. (2005) The Journal of biological chemistry 280, 34447-57. PMID: 16087679 6. Sever-Chroneos, Z. et al. (2011) The Journal of biological chemistry 286, 4854-70. PMID: 21123169 7. De Masson, A. et al. (2016) Oncoimmunology 5, e1127493. PMID: 27467939
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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データシート

Anti-Human CD245/MYO18A Recombinant Antibody (DY12), APC.pdf

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Anti-Human CD245/MYO18A Recombinant Antibody (DY12), APC (HV061137)

概要

イメージ

参考文献

データシート

SDS

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