Anti-Human CD245/MYO18A Recombinant Antibody (DY12) (HV061107)

Name: Anti-Human CD245/MYO18A Recombinant Antibody (DY12)
Brand: abinScience
SKU: HV061107
Price: 191 USD
Availability: InStock

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Número de catálogo	HV061107
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	DY12
Objetivo	CD245, Myosin containing a PDZ domain, MAJN, SP-R210, Surfactant protein receptor SP-R210, MYO18A, MYSPDZ, Unconventional myosin-XVIIIa, KIAA0216, Molecule associated with JAK3 N-terminus
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q92614
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Unconventional myosin-XVIIIa (CD245/MYO18A) is a ~233 kDa protein. May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. 1. Dippold, HC. et al. (2009) Cell 139, 337-51. PMID: 19837035 2. Ng, MM. et al. (2013) Molecular biology of the cell 24, 796-808. PMID: 23345592 3. Tan, I. et al. (2008) Cell 135, 123-36. PMID: 18854160 4. Yang, L. et al. (2015) PloS one 10, e0126576. PMID: 25965346 5. Yang, CH. et al. (2005) The Journal of biological chemistry 280, 34447-57. PMID: 16087679 6. Sever-Chroneos, Z. et al. (2011) The Journal of biological chemistry 286, 4854-70. PMID: 21123169 7. De Masson, A. et al. (2016) Oncoimmunology 5, e1127493. PMID: 27467939
Nota	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human CD245/MYO18A Antibody (DY12)

Referencias

Datasheet

Anti-Human CD245/MYO18A Recombinant Antibody (DY12).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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