Anti-Human Endosialin/CD248 Recombinant Antibody (SAA0182), PE (HV681127)

Name: Anti-Human Endosialin/CD248 Recombinant Antibody (SAA0182), PE
Brand: abinScience
SKU: HV681127
Price: 290 USD
Availability: InStock

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Каталожный номер	HV681127
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	SAA0182
Конъюгация	PE
Цель	Endosialin, TEM1, CD164L1, Tumor endothelial marker 1, CD248
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PE
Номер доступа	Q9HCU0
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Endosialin (CD248) is a ~80 kDa protein. Cell surface glycoprotein involved in various biological processes including angiogenesis, immune response modulation, and tissue remodeling and repair. Participates in pericyte proliferation through positive modulation of the PDGF receptor signaling pathway. Acts as a scaffold for factor X, triggering allosteric changes and the spatial re-alignment of factor X with the TF-factor VIIa complex, thereby enhancing coagulation activation. Modulates the insulin signaling pathway by interacting with insulin receptor/INSR and by diminishing its capacity to be autophosphorylated in response to insulin. Also regulates LPS-induced inflammatory response in macrophages by favoring the production of proinflammatory cytokines. 1. Tomkowicz, B. et al. (2010) Cancer biology & therapy 9, 908-15. PMID: 20484976 2. Hardie, DL. et al. (2011) Immunology 133, 288-95. PMID: 21466550
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.