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| カタログ番号 | HV781013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1966 | ||||
| ターゲット | TRAIL-R4, TRAIL receptor 4, DcR2, TRAIL receptor with a truncated death domain, TRUNDD, DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAILR4, TNFRSF10D, Tumor necrosis factor receptor superfamily member 10D, CD264 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9UBN6 | ||||
| RRID | Anti-Human CD264/TNFRSF10D/TRAIL-R4 Antibody (SAA1966) (abinScience Cat# HV781013, RRID:AB_3727730) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Tumor necrosis factor receptor superfamily member 10D (CD264/TNFRSF10D) is a ~41 kDa protein. Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. 1. Degli-Esposti, MA. et al. (1997) Immunity 7, 813-20. PMID: 9430226 2. Pan, G. et al. (1998) FEBS letters 424, 41-5. PMID: 9537512 3. Marsters, SA. et al. (1997) Current biology : CB 7, 1003-6. PMID: 9382840 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD264/TNFRSF10D/TRAIL-R4 Antibody (SAA1966)
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