Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A633) (HY350015)

Name: Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A633)
Brand: abinScience
SKU: HY350015
Price: 106 USD
Availability: InStock

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Numéro de catalogue	HY350015
Description	Anti-Human CD271/NGFR Monoclonal Antibody (1A633) [1A633] (HY350015) is a mouse monoclonal antibody detecting CD271 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, IHC, WB
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG
ID de clone	1A633
Immunogène	Mammalian cells - derived recombinant human CD271/NGFR (Met1-Asn250).
Cible	Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR, p75 ICD, CD271, NGFR
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P08138
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Tumor necrosis factor receptor superfamily member 16 (CD271/NGFR) is a ~45 kDa protein. Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. 1. Glerup, S. et al. (2014) Neuron 82, 1074-87. PMID: 24908487 2. Lin, Z. et al. (2015) eLife 4, e11692. PMID: 26646181 3. Baeza-Raja, B. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 10221-34. PMID: 23785138 4. Li, H. et al. (2012) Science China. Life sciences 55, 367-74. PMID: 22566094
Note	For research use only.

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Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A633).pdf

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Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A633) (HY350015)

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