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Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A634) (HY350025)

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Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A634)
Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A634)
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Vista general
Número de catálogoHY350025
Descripción
Anti-Human CD271/NGFR Monoclonal Antibody (1A634) [1A634] (HY350025) is a mouse monoclonal antibody detecting CD271 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG
ID de clon1A634
Inmunógeno Mammalian cells - derived recombinant human CD271/NGFR (Met1-Asn250).
Objetivo Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR, p75 ICD, CD271, NGFR
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P08138
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Tumor necrosis factor receptor superfamily member 16 (CD271/NGFR) is a ~45 kDa protein. Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA.

1. Glerup, S. et al. (2014) Neuron 82, 1074-87. PMID: 24908487
2. Lin, Z. et al. (2015) eLife 4, e11692. PMID: 26646181
3. Baeza-Raja, B. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 10221-34. PMID: 23785138
4. Li, H. et al. (2012) Science China. Life sciences 55, 367-74. PMID: 22566094
Nota For research use only.
Imágenes
  • Anti-Human NGFR/TNFRSF16/p75NTR Monoclonal Antibody (1A634)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD271/NGFR Monoclonal Antibody (1A634)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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