Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE (HV375127)

Name: Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE
Brand: abinScience
SKU: HV375127
Price: 290 USD
Availability: InStock

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Каталожный номер	HV375127
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG4, kappa
ID клона	SAA0087
Конъюгация	PE
Цель	B- and T-lymphocyte attenuator, BTLA, CD272, B- and T-lymphocyte-associated protein
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), PE
Номер доступа	Q7Z6A9
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. _x005F_x000D_ _x005F_x000D_ 1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776 _x005F_x000D_ _x005F_x000D_ 2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006 _x005F_x000D_ _x005F_x000D_ 3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026 _x005F_x000D_ _x005F_x000D_ 4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 _x005F_x000D_ _x005F_x000D_ 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow cytometry

Flow-cytometry PE using anti-human CD272 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human CD272 monoclonal antibody (Catalog HV375127) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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