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| カタログ番号 | HV612023 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human CD276/B7-H3 Nanobody (SAA2193) [SAA2193] (HV612023) is a alpaca monoclonal antibody detecting B7-H3 in ELISA. Suitable for Human.
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| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Alpaca | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | VHH-6His | ||||
| クローンID | SAA2193 | ||||
| ターゲット | 4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q5ZPR3 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | CD276 antigen (B7-H3) is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. CD276 is the therapeutic target of omburtamab (clinical). | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD276/B7-H3 Nanobody (SAA2193)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
