

| Каталожный номер | HV612023 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-Human CD276/B7-H3 Nanobody (SAA2193) [SAA2193] (HV612023) is a alpaca monoclonal antibody detecting B7-H3 in ELISA. Suitable for Human.
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| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Alpaca | ||||
| Клоональность | Monoclonal | ||||
| Изотип | VHH-6His | ||||
| ID клона | SAA2193 | ||||
| Цель | 4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule | ||||
| Уровень эндотоксинов | < 10 EU/mg | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q5ZPR3 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | CD276 antigen (B7-H3) is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. CD276 is the therapeutic target of omburtamab (clinical). | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human CD276/B7-H3 Nanobody (SAA2193)




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