

| Número de catálogo | HV987014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human CD312/ADGRE2 Polyclonal Antibody (HV987014) is a rabbit polyclonal antibody detecting CD312/ADGRE2/EMR2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CD312/ADGRE2 (Asn347-Ser509). | ||||||||
| Objetivo | EMR2, EGF-like module receptor 2, ADGRE2, EGF-like module-containing mucin-like hormone receptor-like 2, Adhesion G protein-coupled receptor E2, CD312 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9UHX3 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Adhesion G protein-coupled receptor E2 (CD312/ADGRE2) is a ~90 kDa protein. Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation. 1. Boyden, SE. et al. (2016) The New England journal of medicine 374, 656-63. PMID: 26841242 | ||||||||
| Nota | For research use only. |


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