Anti-Human NKG2D/CD314 Recombinant Antibody (SAA0098) (HB123107)

Name: Anti-Human NKG2D/CD314 Recombinant Antibody (SAA0098)
Brand: abinScience
SKU: HB123107
Price: 163 USD
Availability: InStock

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Numéro de catalogue	HB123107
Reactivité des espèces	Human
Applications	FCM
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG4, kappa
ID de clone	SAA0098
Cible	KLRK1, NKG2D, Killer cell lectin-like receptor subfamily K member 1, NKG2-D-activating NK receptor, D12S2489E, NKG2-D type II integral membrane protein, NK cell receptor D, CD314
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P26718
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~25 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
Note	For research use only.