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| カタログ番号 | HV533013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1634 | ||||
| ターゲット | QA79 membrane protein, Adhesion inhibitory receptor molecule 1, D-siglec, CDw328, Siglec-7, p75, SIGLEC7, AIRM-1, Sialic acid-binding Ig-like lectin 7, CD328, AIRM1 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9Y286 | ||||
| RRID | Anti-Human CD328/SIGLEC7 Antibody (SAA1634) (abinScience Cat# HV533013, RRID:AB_3727395) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Sialic acid-binding Ig-like lectin 7 (CD328/SIGLEC7) is a ~51 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD328/SIGLEC7 Antibody (SAA1634)
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