Anti-Human CD349/FZD9 Recombinant Antibody (2933#) (HT468107)

Name: Anti-Human CD349/FZD9 Recombinant Antibody (2933#)
Brand: abinScience
SKU: HT468107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HT468107
Reactivité des espèces	Human
Applications	FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	2933#
Cible	FzE6, Frizzled-9, FZD9, FZD3, hFz9, CD349, Fz-9
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	O00144
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Frizzled-9 (CD349/FZD9) is a ~64 kDa protein. Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. 1. Chailangkarn, T. et al. (2016) Nature 536, 338-43. PMID: 27509850
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human CD349/FZD9 Antibody (2933#)

Reférences

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Anti-Human CD349/FZD9 Recombinant Antibody (2933#).pdf

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Formula

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