Anti-Human CD349/FZD9 Recombinant Antibody (2933#) (HT468107)

Name: Anti-Human CD349/FZD9 Recombinant Antibody (2933#)
Brand: abinScience
SKU: HT468107
Price: 191 USD
Availability: InStock

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Обзор

Каталожный номер	HT468107
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	2933#
Цель	FzE6, Frizzled-9, FZD9, FZD3, hFz9, CD349, Fz-9
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	O00144
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Frizzled-9 (CD349/FZD9) is a ~64 kDa protein. Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. 1. Chailangkarn, T. et al. (2016) Nature 536, 338-43. PMID: 27509850
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human CD349/FZD9 Antibody (2933#)

Ссылки

Даташит

Anti-Human CD349/FZD9 Recombinant Antibody (2933#).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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