Anti-Human CD350/FZD10 Recombinant Antibody (ONC-005), FITC (HV512117)

Name: Anti-Human CD350/FZD10 Recombinant Antibody (ONC-005), FITC
Brand: abinScience
SKU: HV512117
Price: 223 USD
Availability: InStock

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Número de catálogo	HV512117
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	ONC-005
Conjugación	FITC
Objetivo	FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Número de acceso	Q9ULW2
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Imágenes

Flow cytometry

Flow-cytometry FITC using anti-human CD350 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human CD350 monoclonal antibody (Catalog HV512117) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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