Anti-Human Frizzled-10 Recombinant Antibody (ONC-005) (HV512107)

Name: Anti-Human Frizzled-10 Recombinant Antibody (ONC-005)
Brand: abinScience
SKU: HV512107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV512107
Reactivité des espèces	Human
Applications	ELISA, FCM, IHC, IP, RIA
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	ONC-005
Cible	FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9ULW2
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.
Note	For research use only.