Anti-Human Frizzled-10 Recombinant Antibody (ONC-005) (HV512107)

Name: Anti-Human Frizzled-10 Recombinant Antibody (ONC-005)
Brand: abinScience
SKU: HV512107
Price: 191 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HV512107
種反応性	Human
アプリケーション	ELISA, FCM, IHC, IP, RIA
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	ONC-005
ターゲット	FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q9ULW2
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.
注意事項	For research use only.