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Anti-Human CD355/CRTAM Recombinant Antibody (5A11) (HF645107)

Anti-Human CD355/CRTAM Recombinant Antibody (5A11)
Anti-Human CD355/CRTAM Recombinant Antibody (5A11)
Anti-Human CD355/CRTAM Recombinant Antibody (5A11)
Anti-Human CD355/CRTAM Recombinant Antibody (5A11)
Prix(USD) :
Spécification :
  • 50ug
  • 100ug
Nombre :
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Aperçu
Numéro de catalogueHF645107
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de clone5A11
Cible Class-I MHC-restricted T-cell-associated molecule, Cytotoxic and regulatory T-cell molecule, CD355, CRTAM
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès O95727
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Cytotoxic and regulatory T-cell molecule (CD355/CRTAM) is a ~44 kDa protein. Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T-cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. Regulates CD8+ T-cell proliferation in response to T-cell receptor (TCR) activation. Appears to be dispensable for CD8+ T-cell-mediated cytotoxicity. Interaction with SCRIB promotes the late phase of cellular polarization of a subset of CD4+ T-cells, which in turn regulates TCR-mediated proliferation and IFNG, IL17 and IL22 production.

1. Boles, KS. et al. (2005) Blood 106, 779-86. PMID: 15811952
Note For research use only.
Images
  • Anti-Human CD355/CRTAM Recombinant Antibody (5A11)

    Bioactivity

    Detects CD355/CRTAM in indirect ELISAs.

  • Anti-Human CD355/CRTAM Recombinant Antibody (5A11)

    Western blot

    Western blot analysis was performed using anti-CD355/CRTAM monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD355/CRTAM (Catalog No: HF645011)
    Lane 2: negative control

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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C₂ (Working Conc.)
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Recommandation

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